Welcome To Dr. Igor A. Parshikov`s Page!


Ph.D., Postdoctoral Research Program (2001), NCTR, FDA, Jefferson, AR, USA
Ph.D., Microbiology (1993), Moscow State University
(Title of thesis: "Transformation of N-Containing Heterocyclic Compounds by Some Fungi")
M.S., Microbiology (1985), Moscow State University
(Title of thesis: "Oxidation of N-Containing Heterocycles by Beauveria bassiana ATCC 7159")
Scopus Author ID: 6602236624
ResearcherID: J-2666-2015


Publications:
Research manuscripts:


Parshikov I.A., Hernandes-Luna C.E., Zaraisky E.I. Microbial transformation of the antimalarial and anticancer drug artemisinin by white-rot basidiomycetes. Asian Journal of Microbiology, Biotechnology and Environmental Sciences. 2018. V. 20. N 4. P. 1093-1096.


Parshikov I.A., Khasaeva F.M. Fungal transformation of ofloxacin and enrofloxacin. // Asian Journal of Microbiology, Biotechnology and Environmental Sciences. 2018. V. 20. N 2. P. 368-371.


Parshikov I.A., Sutherland J.B. Biotransformation of steroids and flavonoids by cultures of Aspergillus niger. Applied Biochemistry and Biotechnology. 2015. http://dx.doi.org/10.1007/s12010-015-1619-x


Parshikov I.A., Woodling K.A., Sutherland J.B. Biotransformations of organic compounds mediated by cultures of Aspergillus niger. Appl. Microbiol. Biotecnol. 2015. http://dx.doi.org/10.1007/s00253-015-6765-0


Parshikov I.A., Sutherland J.B. The use of Aspergillus niger cultures for biotransformation of terpenoids. Process Biochemistry. 2014. V.49. N 12. P. 2086-2100. http://dx.doi.org/10.1016/j.procbio.2014.09.005


Silva E.O., Carvalho T.C., Parshikov I.A., Santos R.A., Emery F.S., Furtado N.A.J.C. Cytotoxicity of lapachol metabolites produced by probiotics. Letters in Applied Microbiology. 2014. V.59. N 1. P.108-114.


Khasaeva F.M., Zakharchuk L.M., Netrusov A.I., Parshikov I.A. Biodegradation of pyridine by Arthrobacter sp. Natural Science. In: Young Scientist USA. 2014. V.1, P.50-52. http://doi.org/10.17686/sced_rusnauka_2014-1127


Parshikov Igor A., Silva Eliane O., Furtado Niege A. J. C. Transformation of saturated nitrogen-containing heterocyclic compounds by microorganisms. Appl. Microbiol. Biotecnol. 2014. V.98. N 4. P.1497-1506.


Parshikov I.A., Sutherland J.B. Microbial transformations of antimicrobial quinolones and related drugs. J. Ind. Microbiol. Biotechnol. 2012, v.39, N 12, P.1731-1740.


Parshikov I.A., Netrusov A.I., Sutherland J.B. Microbial transformation of azaarenes and potential uses in pharmaceutical synthesis. Appl. Microbiol. Biotecnol. 2012, v.95, N 4, P.871-879. http://dx.doi.org/10.1007/s00253-012-4220-z


Parshikov I.A., Netrusov A.I., Sutherland J.B. Microbial transformation of antimalarial terpenoids. Biotech. Adv. 2012, v. 30, P.1516-1523.


Parshikov I.A., Terentyev P.B., Modyanova L.V., Hofmann H., Haufe G., Fogel M. Microbiological synthesis of 4-hydroxy-5-isopropyl-5-methoxy-2-oxo-2,5-dihydrofuran. ChemInform. 2010, v.26, N 10.


Williamson J. S., Parshikov I. A.,Avery M. A. Biotransformations of Artemisinin. in: - Recent Progress in Medicinal Plants, (Phytochemistry and Pharmacology). 2007, v. 17, P. 115-138.


Parshikov IA, Miriyala B, Muraleedharan KM, Avery MA, Williamson JS. Microbial transformation of artemisinin by Eurotium amstelodami and Aspergillus niger. J Ind Microbiol Biotechnol. 2006, v. 33, N5, P. 349-352.


Parshikov I. A., Miriyala B., Muralieedharan K. M., Illendula A., Avery M. A., Williamson J. S. Biocatalysis of the antimalarial artemisinin by Mucor ramannianus strains. Pharm. Biol., 2005, v. 43, N7, P. 579-582.


Parshikov I. A., Miriala B., Avery M. A., Williamson J. S. Hydroxylation of 10-deoxoartemisinin to 15-hydroxy-10-deoxoartemisinin by Aspergillus niger. Biotechnol. Lett. 2004, v. 26, N7, P. 607-610.


Parshikov I. A., Muralieedharan K. M., Avery M. A., Williamson J. S. Transformation of artemisinin by Cunninghamella elegans. Appl. Microbiol. Biotechnol., 2004, v. 64, N6, P. 782-786.


Parshikov I. A., Muralieedharan K. M., Avery M. A., Williamson J. S. Hydroxylation of 10-deoxoartemisinin by Cunninghamella elegans. J. Nat. Prod., 2004, v.67, N9, P. 1595-1597.


Williams A. J., Parshikov I. A., Moody J. D., Heinze T. M., Sutherland J. B. Fungal transformation of the antimicrobial agent during growth on poultry-litter materials. J. Appl. Poultry Res., 2004, v. 13, N 2, P. 235-240.


Sutherland J. B., Freeman J. P., Heinze T. M., Moody J. D., Williams A. J., Parshikov I. A., Zhang D. Oxidation of phenothiazine and phenoxazine by Cunninghamella elegans, Xenobiotica, 2001, v. 31, P.799-809.


Parshikov I. A., Heinze T. M., Moody J. D., Freeman J. P., Williams A. J., Sutherland J. B. The fungus Pestalotiopsis sp. as a model for biotransformation of ciprofloxacin and norfloxacin. Appl. Microbiol. Biotechnol., 2001, v. 56, No.3/4, P. 474-477.


Parshikov, I. A., Heinze T. M., Williams A. J., Moody J. D., Freeman J. P., Sutherland J. B. Biotransformation of the antibacterial agent cinoxacin by the fungus Beauveria bassiana. FEMS Microbiol. Lett.,
2002, v.214, P.133-136.


Parshikov I. A., Freeman J. P., Lay J. O. Jr., Moody J. D., Williams A. J., Beger R. D., Sutherland J. B. Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus. J. Ind. Microbiol. Biotechnol., 2001, v. 26, P.140-144.


Parshikov I. A., Freeman J. P., Lay J. O. Jr., Beger R. D., Williams A. J., Sutherland J. B. Microbiological transformation of enrofloxacin by the fungus Mucor ramannianus. Appl. Environ. Microbiol., 2000, v. 66, No. 6. P. 2664-2667.


Parshikov I. A., Freeman J. P., Lay J. O. Jr., Moody J. D., Williams A. J., Sutherland J. B. Formation of unusual ciprofloxacin and norfloxacin conjugates by the fungus Trichoderma sp. Mycologia, 2002, v.94, P.1-5.


Parshikov I. A., Freeman J. P., Lay J. O. Jr., Beger R. D., Williams A. J., Sutherland J. B. Regioselective transformation of ciprofloxacin to N-acetylciprofloxacin by the fungus Mucor ramannianus. FEMS Microbiol. Lett., 1999, v. 177, P. 131-135.


Parshikov I. A., Freeman J. P., Williams A. J., Moody J. D., Sutherland J. B. Biotransformation of N-acetylphenothiazine by fungi. Appl. Microbiol. Biotechnol., 1999, v. 52, P. 553-557.


Modyanova L.V., Duduchava M.R., Piskunkova N.F., Grishina G.V., Terentyev P.B., Parshikov I.A. Microbial transformations of piperideine and pyridine derivatives. Chemistry of Heterocyclic Compounds, 1999, v. 33, N5, P. 580-586; Chemical Abstracts, v. 132, 166096.


Terentyev P.B., Parshikov I.A., Grishina G.V., Piskunkova N.F., Chumakov T.I., Bulakhov G.A. Hydroxylation of double bond in 1-benzyl-3-methylpiperideine by mycelial fungi. Chemistry of Heterocyclic Compounds, 1997, v. 33, N5,619-620.


Parshikov I.A., Terentyev P.B., Piskunkova N.F., Gracheva G.A., Bulakhov G.A. Micobiological transformation of derivatives 4-phenyl-2-pyrrolidone by mycelial fungi. Chemistry of Heterocyclic Compounds, 1997, v. 33, N5, 523-526.


Parshikov I.A., Terentyev P.B., Modyanova L.V., Duduchava M.R., Dovgilevich E.V., Butakoff K.A. Microbial transformation of 9-amino-1,2,3,4,5,6,7,8-octahydroacridine. Chemistry of Heterocyclic Compounds, 1994, v. 30, N5, 627-628; Chemical Abstracts 1995, v. 122, 290697j.


Parshikov I.A., Terentyev P.B., Modyanova L.V., Khofmann K., Khaufe G., Vogel M. Microbiological synthesis of 4-hydroxy-5-isopropyl-5-methoxy-2-oxo-2,5-dihydrofuran. Chemistry of Heterocyclic Compounds, 1994, v. 30, N5,626; Chemical Abstracts 1995, v. 122, 290613d.


Parshikov I.A., Terentyev P.B., Modyanova L.V. Microbiological transformation in a series of nitrogen containing-heterocycles. (Review.) Chemistry of Heterocyclic Compounds, 1994, v. 30, N11-12, 1308-1330; Chemical Abstracts 1995, v.122, 290732s.


Parshikov I.A., Modyanova L.V., Dovgilevich E.V., Terentyev P.B., Vorobyeva L.I., Grishina G.V. Microbial transformations of nitrogen heterocycles. III. Microbial synthesis of 1-benzoylpiperidine and 1-benzoylpyrrolidine hydroxy derivatives. Chemistry of Heterocyclic Compounds, 1992 , v. 28, N 2, P. 159-162; Chemical Abstracts 1993, v. 118, 6835c.


Kostrikin Yu. M., Pil'tsova N.K., Vorob'eva L.I., Parshikov I.A., Chaplygina A.P. Biological factor of nitrite formation in feeding water of boilers. Energetik (in Russian), 1991, N 5, P. 24-25; Chemical Abstracts v.115, 166276.


Dovgilevich E.V., Parshikov I.A., Modyanova L.V., Terent'ev P.B., Bulakhov G. A. A novel microbial transformation of gamma-carboline derivative 3,6-dimethyl-9-[2-(2-methylpyrid-5-yl)ethyl]-1,2,3,4-tetrahydro-gamma-carboline. Mendeleev Commun. 1991, N2, P.42-43; Chemical Abstracts 1992, v. 116, 102363b.


Parshikov I.A., Bol'shova N.I., Simonova L.N., Parshikova V.V. Studeing of bacteria isolated in the Kondopozhskii paper mill. Trudy TsNIIB, 1988, Moscow, P.113-119; Chemical Abstracts 1989, v. 110, P151102a.


Parshikov I.A., Vasichkina H.I., Simonova L.N., Bol'shova N.I. Slime control in paper industry. Cellulose, Paper and Cardboard, N 7, Moscow; VNIPIEIlesprom, (in Russian), 1986, 32 pp., (Review).


Patents:

Parshikov I.A., Vorobyeva L.I., Modyanova L.V., Dovgilevich E.V., Terentyev P.B., Khofmann K. Strain of fungus Cunninghamella verticillata VKPM F-430 as a transformator for 1-benzoylpyrrolidine and 1-benzoylamino-3,7-dimethyloctadiene-2,6 hydroxylation. USSR Inventor's Certificate N 1 789 557, 1990 (Cl. C12P 17/12, C12N 1/14).


Parshikov I.A., Vorobyeva L.I., Modyanova L.V., Dovgilevich E.V., Terentyev P.B., Khofmann K. Strain of fungus Beauveria bassiana VKM F-3111D as a transformator for 1-benzoylpiperidine and 1-benzoylamino-3,7-dimethyloctadiene 2,6-hydroxylation, USSR Inventor's Certificate N 1 822 886, 1990 (Cl. C12P 17/12, C12N 1/14); Chemical Abstracts 1995, v. 122, 289065v.


Dovgilevich E.V., Modyanova L.V., Parshikov I.A., Terentyev P.B., Vorobyeva L.I., Bundel Yu.G. The method of obtaining (-)-(1-hydroxyethyl)pyridines, USSR Inventor's Certificate N 1 364 621, 1987 (Cl. C07D 213/30, C12P 100, C12R 1:645); Chemical Abstracts 1988, v.109, 91269c.


Vorob'eva L.I., Parshikov I.A., Ol'sinskaya N.L., Bol'shova N.I., Parshikova V.V. Method for manufacturing levanhydrolase, a slime-decomposing compound. USSR Inventor's Certificate N 1542956, 1989 (Cl. C12N 9/14); Chemical Abstracts 1990, v. 113, P150881d.


Parshikov I.A., Simonova L.N., Vasichkina H.I., Agapova L.M., Boev V.S., Fetisova L.E., Bol'shova N.I. A fungicide composition for slime control, USSR Inventor's Certificate N 1542912, 1987 (Cl. C02F 1/50); Chemical Abstracts 1990, v. 112, P223097u.


Parshikov I.A., Vasichkina H.I., Simonova L.N., Bol'shova N.I., Pshenichnikov V.S., Bondar' A.A., Zavatskii V.N., Gevaza Yu.I., Golik G.A. Prevention of slime formation. USSR Inventor's Certificate N 1451100, 1986 (Cl. C02F 1/50, E21B 43/22); Chemical Abstracts 1989, v. 111, P12111k.


Books:

Parshikov I.A. Microbial conversions of nitrogenous heterocycles. 2015. M.: Editus, 130 p. (ISBN: 978-5-00058-198-8)


Parshikov I.A. Microorganisms in Chemistry of Terpenoids. – Dallas: Primedia E-launch LLC, 2016. − 102 p. (ISBN 978-1-68419-775-0)


Parshikov I.A. Methods of Biotechnology in the Synthesis of Drugs. – 2nd. Edition. – Dallas: Primedia E-launch LLC, 2018. −120 p. ISBN 978-1-68454-785-2


Parshikov I.A. . Features of Antitumor and Antimalarial Artemisinins Biotransformations. – Dallas: Primedia E-launch LLC, 2018. − 30 p.


Parshikov I.A. Biotransformaciones de Antitumorales y Antimalariales Artemisininas. – Dallas: Primedia E-launch LLC, 2019. − 30 p. ISBN 978-1-64713-017-6


Abstracts:

Parshikov I. A., Miriyala B., Hernandez-Luna C.E., Avery M. A., Williamson J. S. Regiocelective Transformation of Artemisinin by White-Rot Basidiomycetes. 106th General Meeting of American Society for Microbiology, Orlando, FL, May 21-25, 2006, Q-293.


Parshikov I. A., Miriyala B., Avery M. A., Williamson J. S. Transformation of Artemisinin by Different Strains of Mucor ramannianus. 105th General Meeting of American Society for Microbiology, Atlanta, GA, June 5-9, 2005, Q-198.


Parshikov I. A., Miriyala B., Avery M. A., Williamson J. S. Transformations of artemisinin to 5-hydroxyartemisinin. Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005, #381.


Parshikov I. A., Miriyala B., Muralieedharan K. M., Avery M. A., Williamson J. S. Fungal transformations of artemisinin. 104th General Meeting of American Society for Microbiology, New Orleans, LA, May 23-27, 2004, Q-286.


Parshikov I. A., Muralieedharan K. M., Avery M. A., Williamson J. S. Novel microbial transformations of artemisinin and 10-deoxoartemisinin. 103th General Meeting of American Society for Microbiology, Washington, D.C., Maryland, May 18-22, 2003, Q-129.


Muraleedharan, K. M.; Parshikov, I. A.; Bandyopadhyaya, A. K.; Desai, P. V.; Tekwani, B. L.; Avery, M. A. Artemisinin-based antimalarial drugs: Search for new derivatives with improved bioavailability and novel biological activities. Abstracts of Papers, 225th ACS National Meeting, New Orleans, LA, United States, March 23-27, 2003.


Parshikov I. A., Heinze T. M., Moody J. D., Williamson J. S. Microbial N-fornylation and N-acetylation of the Antimalarial drug Primaquine (8-Aminoquinoline). National Center for Natural Products Research - School of Pharmacy - Internal Poster Session -2002, University, Mississippi, October 04, 2002, #35.


Parshikov I. A., Avery M. A., Williamson J. S. Microbial transformation of the Artemisinin by fungi. 2nd Research Meeting of the Consortium for Antimalarial Development, University, Mississippi, E. F. Yerby Conference Center, August 23, 2002.


Parshikov I. A., Heinze T. M., Moody J. D., Williamson J. S. Microbial transformation of the Antimalarial drug Primaquine (8-Aminoquinoline) by Beauveria bassiana. 102th General Meeting of American Society for Microbiology, Salt Lake City, Utah, May 19-23, 2002, Q-83.


Parshikov, I. A., Heinze T. M., Williams A. J., Moody J. D., Freeman J. P., Sutherland J. B. Biotransformation of the antibacterial agent cinoxacin by the fungus Beauveria bassiana. 102th General Meeting of American Society for Microbiology, Salt Lake City, Utah, May 19-23, 2002, Q-78.


Williams A. J., Parshikov I. A., Moody J. D., Heinze T. M., Freeman J. P., Sutherland J. B. The metabolism of two antibacterial agents, norfloxacin and sarafloxacin by the saprobic fungus Trichoderma sp. during growth on the rise hulls. 101th General Meeting of American Society for Microbiology, Orlando, Florida, May 20-24, 2001, Q-195.


Parshikov I. A., Heinze T. M., Moody J. D., Freeman J. P., Williams A. J., Sutherland J. B. Regioselective formation of N-oxides from enrofloxacin and ofloxacin by the fungus Rhizoctonia sp. 101th General Meeting of American Society for Microbiology, Orlando, Florida, May 20-24, 2001, Q-192.


Parshikov I. A., Heinze T. M., Moody J. D., Freeman J. P., Williams A. J., Sutherland J. B. The fungus Pestalotiopsis sp. as a model for biotransformation of ciprofloxacin and norfloxacin. 101th General Meeting of American Society for Microbiology, Orlando, Florida, May 20-24, 2001, Q-191.


Parshikov I. A., Freeman J. P., Lay J. O. Jr., Moody J. D., Williams A. J., Beger R. D., Sutherland J. B. Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus. 100th General Meeting of American Society for Microbiology, Los Angeles, California, May 21-25, 2000, Q-182.


Parshikov I. A., Freeman J. P., Lay J. O. Jr., Beger R. D., Williams A. J., Sutherland J. B. Microbiological transformation of enrofloxacin by the fungus Mucor ramannianus. 100th General Meeting of American Society for Microbiology, Los Angeles, California, May 21-25, 2000, Q-180.


Parshikov I. A., Freeman J. P., Williams A. J., Moody J. D., Sutherland J. B. Microbiological transformation of N-acetylphenothiazine by fungi. 99th General Meeting of American Society for Microbiology, Chicago, Illinois, May 30 - June 3, 1999, Q-258.


Parshikov I. A., Freeman J. P., Lay J. O. Jr., Moody J. D., Williams A. J., Sutherland J. B. Formation of unusual ciprofloxacin and norfloxacin conjugates by the fungus Trichoderma sp. 100th General Meeting of American Society for Microbiology, Los Angeles,California, May 21-25, 2000, Q-181.


Parshikov I. A., Freeman J. P., Lay J. O. Jr., Moody J. D., Williams A. J., Beger R. D., Sutherland J. B. Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus. 100th General Meeting of American Society for Microbiology, Los Angeles, California, May 21-25, 2000, Q-182.


Khaufe G., Dorre M., Khofmann H., Weber L., Parshikov I.A. Microbial transformation of substituted terpenoids of fungi. XIVth Conference on Isoprenoids, Tabor, Czecho-Slovakia, September 15-21, 1991, P. 47.


Dovgilevich E. V., Modyanova L. V., Parshikov I. A., Terentyev P. B., Duduchava M. R. Microbial synthesis of N-oxide of 9 amino-1,2,3,4,5,6,7,8-octahydroacridine: All-Union Conference on Chemistry of N-containing heterocyclic compounds. Chernogolovka, Moscow region, Russia, 1991, part 1, P. 118.


Terentyev P. B., Parshikov I. A., Dovgilevich E. V., Vorobyeva L. I., Modyanova L. V., Grishina G. V. Microbiological synthesis of isomeric hydroxy-1-benzoylpiperidines: Conference on "Chemistry of physiologically active compounds". Chernogolovka, Moscow region, Russia, November 13-15, 1989. P. 226.


Parshikov I. A., Alvares H. B. Screening of microscopic fungi that transform N-containing heterocyclic compounds. 20th Meeting of Young Scientists, Moscow State University, Moscow, Russia, April 24-28, 1989, part 2, P. 78-92.


Parshikov I. A., Dovgilevich E. V., Modyanova L. V., Vorobyeva L. I., Terentyev P. B. Stereoselective hydroxylation of ethylpyridines. Conference on asymmetric compounds. Telavi, Georgia, FSU, October 12-14, 1989. P. 47.


Dovgilevich E.V., Modyanova L.V., Parshikov I.A., Terentyev P.B., Bundel U.G. The method of obtaining (-)-(1-hydroxyethyl)pyridines. 4th Meeting of Organic Chemistry and Technologies of All-Union Chemical Society of D.I. Mendeleev. Moscow, USSR, November 12-14, 1985, P. 104.




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